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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENPP3 All Species: 31.52
Human Site: T846 Identified Species: 69.33
UniProt: O14638 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14638 NP_005012.2 875 100124 T846 V R D V E L L T G L D F Y Q D
Chimpanzee Pan troglodytes XP_518741 875 100145 T846 V R D V E L L T G L D F Y Q D
Rhesus Macaque Macaca mulatta XP_001103445 874 99855 T845 V R D V E L L T G L D F Y Q D
Dog Lupus familis XP_532050 889 102239 T860 V R D V E L L T G L D F Y Q E
Cat Felis silvestris
Mouse Mus musculus Q6DYE8 874 98630 T845 V R D V E L L T G L D F Y Q E
Rat Rattus norvegicus P97675 875 99053 T846 V R D V E L L T G L D F Y Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505967 868 99060 T839 V R D V E L L T G L D F Y Q E
Chicken Gallus gallus XP_424539 912 103729 T884 V R D I E L L T G L S F Y Q D
Frog Xenopus laevis Q6AX80 452 51293 C423 M V L T T L T C I I I M L K K
Zebra Danio Brachydanio rerio Q566N0 459 51584 L431 T F T C L F K L M K N R N V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P90754 829 93146 F797 L D Y T A T I F D V E R I S G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97 80.6 N.A. 80.6 81.4 N.A. 69.5 51.4 20.9 21.3 N.A. N.A. N.A. 24.9 N.A.
Protein Similarity: 100 99.6 98.2 88.4 N.A. 90.4 90.1 N.A. 82.5 67 34.6 34.7 N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 86.6 6.6 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 26.6 6.6 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 10 73 0 0 0 0 0 10 0 64 0 0 0 37 % D
% Glu: 0 0 0 0 73 0 0 0 0 0 10 0 0 0 37 % E
% Phe: 0 10 0 0 0 10 0 10 0 0 0 73 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 73 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 10 0 10 10 10 0 10 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 10 0 0 0 10 10 % K
% Leu: 10 0 10 0 10 82 73 10 0 73 0 0 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 % Q
% Arg: 0 73 0 0 0 0 0 0 0 0 0 19 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % S
% Thr: 10 0 10 19 10 10 10 73 0 0 0 0 0 0 0 % T
% Val: 73 10 0 64 0 0 0 0 0 10 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 73 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _